Dr. Milan Bera

Associate Editor: Innovation of Chemistry & Materials for Sustainability

Welcome to PSML Group

PSML group is dedicated to providing high-quality research output in synthetic organic chemistry. Our team is committed to delivering valuable insights and solutions.

Our Research Focus

Creating sustainable synthetic and catalytic methods to activate small molecules is our core focus. Our research aims to innovate in the activation & functionalization of inert C-H, C-C, and C-heteroatom bonds, reducing reliance on stoichiometric metal complexes. We strive to develop new methodologies that produce diverse, relevant molecular architectures. Additionally, we delve into the mechanisms of these reactions to establish a foundation for future applications in chemistry.

Featured Publications

Hydrogen-Bonding Network-Enabled Terminal Selective Heteroarylation of Allenamides in Hexafluoroisopropanol

Hexafluoroisopropanol (HFIP)-mediated terminal selective heteroarylation of allenamides has been accomplished through H-bonding network-enabled substrate activation in a robust fashion. This strategy features a cascade process involving sequential nucleophilic addition followed by electrophilic heteroaromatic substitution and is well suited for late-stage functionalization of complex bioactive molecules. The elucidation of the underlying mechanism was achieved through a comprehensive combination of several control experiments, kinetic studies, isotopic labeling experiments, and the isolation of the HFIP–allenamide intermediate adduct.

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